Sphingolipids, universal components of biological membranes of all eukaryotic organisms,
from yeasts to mammals, in addition of playing a structural role, also play an important part of
signal transduction pathways. They participate or, also, ignite several fundamental
subcellular signaling processes but, more in general, they directly contribute to key
biological activities such as cell motility, growth, senescence, differentiation as well as cell
fate, ie, survival or death. The sphingolipid metabolic pathway displays an intricate network …